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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '046d32fbde82c2869d130597509247d16aa2ad527e3787d4fab7b0afb3425287' 
  AND token = 'dGog/Ka5CAv8Tgn/qv5ejxTE4O0o6jvaLnTFoyxgIHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}