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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac5e94e8d510649e6f04146cca33d424cd307087ff8568afa2423bf27ca120c5' 
  AND token = 'M5H8K0W4P35+eX0W9Zc2LxYPwLWcBLZv4mn3739MT7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}