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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a258f96f7969afd875e646391ff0dfaff4dfb6a6bdf10cd69d0b558dd25f2401' 
  AND token = 'Nd67mmsMQeYNWCm3r9sWLiN8mNWgdHywPD377rkG0As=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}