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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f6f4c152451bf12d4496f3722885df4f7b2d64dab6f35a8c9a8b9c6c51a72b4' 
  AND token = 'jyIuO3T8QsaP4yUdcixZ87zDaTL3lNi+eFWQIEHAtBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}