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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8b25c3cdc5c2934d256ee5cbe3281257643b218d37b165e6414e12e245ff176' 
  AND token = 'S6PSX/guzn+Xfg128nazvZ9ma5zNXhmhqWZySoJFH/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}