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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af0cdd9bb6422b75be17fc3d3dd0f70b453c1e483852dff1df04d5049605cca3' 
  AND token = 'bCCTQWrD4CbI5VrO11KVtU5RUdlex48xePcrEj0vw/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}