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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9f5556504aacff2e793db221a3c9fd5b384b6b4b1e607f2a09920706a0af5e8' 
  AND token = 'OU2Fnxoyg/8VGeCfyRtk08nHap+bkqAYCeBqJcPxXRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}