SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1defba52bc74d33bcf52aecbed2792efb6eef99fdc1da5efd61e3cf56f7b65e3' 
  AND token = '/gX/K4MR+HfsLEJLMmD8J8zLQLIWbjjy982s4vtNpuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}