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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '878bb0faabab1529f959c3816124938fa991537f0694104b59a8a064168b087a' 
  AND token = 'TtyMLB/KiXsYbQvhrMTMrvpyU9pvHX27obQz3ovc6Q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}