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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c99ef6c03a85351c2802f5bfe58546229bd12f7fdece4d17bd70f1be45237ecb' 
  AND token = 'TOszj1q0aOGcVk15kO/vNMLRzuI4vYfZky1+WGP5CBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}