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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73127eae9f8c1c81d1e8324f23b3df1720425d5b87b34e02a0ac8cda450544ec' 
  AND token = '0g21FasVENH2t4o/or1s9u5kEo8/DkbeS/9tjTEU3po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}