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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc2c1be15b00801643a82f9599439f020534f31c75fc18c2c134f70007fb2e8d' 
  AND token = 'YZBAtcL8kmUuBvEyGpA+kJs3P/7eWFjFs/D2fHVR1WA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}