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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2157edc7cac0b93a0d23086da5cfdf4ad44f1c99d017394e6fbcfc285301744' 
  AND token = '1gSZmbx60aCHQJ/enc2OGef+YuR7nE0X6UoVQ3hVQSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}