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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '516f969af76bd1d945b9544a56f6844493e9bc7c9bd9952e84cff21ba09646f1' 
  AND token = 'MJImyD6oaZAnEppuqHOegr3553v/N6YS+brrwl/rxP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}