SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3241fe5b513e10e45e733a1131b9a96f2c93089ca132a2b1645b19bb6f61779c' 
  AND token = 'N9iZQeuTJ2CaN6vP8KmUP1b2eUDvSR5v6YGMdI87YBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}