SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9ecccb6d93f43c709e422361df970ed9639f7f1a1ee49e7d200a5403fed71e7' 
  AND token = '4L05S7VenhsKZPzwd8qszn9WUB5Pk6EYTaLMLWnETXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}