SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c89c592a6a3dc86cc91e6d882361c6b23c2cc4f953de8f26c02e7338b16d902' 
  AND token = 'd2t7mHgffs2Dp6PFli2uJl6zZG6mhQYETqTZ/sdw7BI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}