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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '892260345022594954bb8758c12e7d9b5fcf93a500dc3629a204224d6c422552' 
  AND token = 'sj+2n0npwMgGpLl5IoU0nHA0XrrvkFbfrmD4o/CJgCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}