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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e821de6dc2346fd5a943039e47f1dd4ed218bc3a50b19455a7062665a9affec' 
  AND token = 'd7YFOP+1U4nd1aYXRLiZ0SiUBRsdZ6g4UiNU5O0YFL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00071

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}