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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d123dd328e120be512062edb8d4e853a090a73ecd76539db91c999316f835e0' 
  AND token = '+BQOeMr67wPRXzRvyU9kBz8EMjc4uy5sUxPzlj4SSnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}