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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19ca0f9227d380cb71e3ce7a65900d7658e76ed8acb5644bcfc62c57081b90d2' 
  AND token = 'PhP9l0WH60728no8ACy6BdaPaNl0H0dkDqgupA9neLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}