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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1e02b7be5d19ec5cce9b73912e4dc43a878bec58aa78559f6913d55e091ad15' 
  AND token = 'J1nV7iugIh0uTXDuySmF42NXXnjZ0SZBGX9xg0CtrIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}