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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03994ba9d4c07426a40177f15320a3f47d45aea4714cf91044b57d1879c24485' 
  AND token = 'x3IoOENUpemnbn4WObRj1sedp72dpuycJvZBLShoAJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}