SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a21fc02067476cedb65830d86e71cb589f4ce21b77d47e158bb6e221789428d' 
  AND token = 'hh4GD2I5gR0Bs+OUHdFb5NRMZhXteBiDa45YAekyxFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}