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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ed65743db38d50deaeb50ace25e9d553928bd32324808e6635a46a403c38460' 
  AND token = 'NZ7ipqv8h9/jjFGkArbYGbsfeL6G3eOvHwfsaEaRX70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}