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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdc665f20ade8c52cb93ac2d8444c103f26ff6382de047657abf518328a05dc6' 
  AND token = 'CN9FrPpbmcYzAzFfN2KwCR/MtP0QQtH+heEeYhr+CMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}