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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2625c321a8a0cdf56a195bfec70b49b06b79bba6c621048a3873fe9a783d1818' 
  AND token = '20XUf4125UmNsz79bdt8VN1yqTrlGpNcmOjZCU3+fPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}