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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '667d6785f1d657f0c40c9f3ac45a515fdcc13d17cdca1a7711d0b823129bfb70' 
  AND token = 'G6TJmfTA8nXlHwIM213jBrhb0pJ9KMfKm9q0HCU3PS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}