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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eea5601d3dac27029a20a629ca9b360be4f6325aea4c6c8fc6b02b63a696d385' 
  AND token = '3Rzs0ACRIGnu3dCT9Esa8qCBhJSdXD+b8rcnbsVJ2ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}