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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6cd1d7d811b5b4558c3bb554e6eaa466b2df2f549239bc39dba23c0bfb7c8e6' 
  AND token = '8OFw8g/WDSsTZqFfq8wXoE3tBB+eU9jn5SBNZedgO9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}