SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eebd4ff3c60a97f8d62cbbbb630235aefe8fc33836b41cc57cb24f634649c2c3' 
  AND token = 'LzqYkH/ANJvKH8bnZCYNY5K1s6mB3kcZxvRFAkSXKiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}