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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e590a8328df3d3661ebd4585012077fb364672a3305dd12b992f0d14485f0612' 
  AND token = 'SVM1yTS28lY0EjdV+dYs3agoNrn/qSOozGm74VVsez8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}