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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cca293a88c746522f30478fa192b81cf1b5cb8986b9d6216251823172831790' 
  AND token = '2E1llOk40Rh7o2hRTQRtnO66jc2KaucrWYzFkHPTbcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}