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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c21b12ebf743d30c3cd1d873cfd5bdee91934309e13a5724717f5fce09561fc7' 
  AND token = 'z21q1F/4BzuSpdr2j1wB38N6BP1VYu6EmZPp81SBWYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}