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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4709a9a4019d8fb6e79c90f31610b91cb2f1c17b573ddb579a19125cb85b84bd' 
  AND token = 'AIXai2n4zg/SCIW7N9jG1fW0CL/El1CW++25M00NMXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}