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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e183844b74092824f828c3051a530dbc344df91c0221cdf6172b4daf3edbfc1' 
  AND token = '28hPM5oCOMNodyn+Ymxgdj48DdbJlXz1lFpeFeApDfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}