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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0ae5fa593adea3bb578172c97d05f116f44b3bbb1434c4926b6c253ce4e12c6' 
  AND token = 'vZfGwsubcZUXwT3/7VXTq+DrJc20bywd1pOcRYTVBZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}