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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e8819bdcf6c48742412eb5d226af31015d02b38c5efe7517c54f15641017a9a' 
  AND token = 'qS7L/X3HgkSqA13/U5FlZG5RW0qT+QnTPXNX5lPtKD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}