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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a34a28ee5b62f12b49abb028e4230edb564edcb165efdad1325b4fb293ea0c3' 
  AND token = 't4/+HCmAAJHIMq6+sZ5AUvW6xKr+Njl4Ng8wWtBCgC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}