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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15bfd9ca05c6283157a0c80ede747ef41810934eccb23f47c105245133b45437' 
  AND token = 'WNTkxvlLMFegjTlX+Xq7LBBd+mY2SxIXvHZ6CocIQo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}