SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b80ae2e1fda409a1c63def0e04d5b6c2f4ee328360f2da432601cc6d6776f530' 
  AND token = 'CEx05d2vA8OJ2e5EmBZ91Ol5k3gAMYZJUDQHFwGX1VM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}