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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2e10c056abe6e85d92d0a714e7580622f6b2224ebefa2440ee3b82b77585283' 
  AND token = 'imGIYVEW9Gb6dwaOQt8qHCSGx3KWHFfuFl2eZGtPxUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}