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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8c736d438907eebb04f4a8534f5a7a33a13b4a3c5f2da056a9920b454e36d05' 
  AND token = 'N+JlfMRjoVofdwaU4idM4lL9wjl8I30kH5v4XSlHTtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}