SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b17c5906c0af32844bb95cabf92a11d0dd414262528cb03d898d6f4fadfa720b' 
  AND token = 'k0vE7BEbKKoZWePKOh6D/oaRH1wjoLi5qvLRIfJMxrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}