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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '337d25d09de26dcc02384bcb19acdcf6a9c99999b93d51a12e4b891d197c0b54' 
  AND token = 'vF0CfGlph3STHtOvbP2jLeQIAtK8B0ojf0Owmm+Q7nQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}