SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a417af92112cca886f13329c60b3037747ba259d12f3fc534c5b1900d43a33a' 
  AND token = 'NIx0eEascGPt8GpBur735MRCNX5cKiCLscqIOvMK/fQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}