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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b744ec4b77bf4e3aadece7f37f59310db3a4f25d6357754b1406984b486c3407' 
  AND token = 'ceo0pNZCoFb6EMLrKz0e7XxzRM0q5hjOqC9MLaxmoHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}