SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52b2214d3a57ea5bbb30d7866f8353fed35ff9c57e848fb6f5d7e9c24ad2b4ec' 
  AND token = '92NIpmHQHWDziHzr1XovSS8gLJBB7+IDYHGi9gfE43Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}