SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f0b5de3e8d29a2d84da9aaa39ac477e5a3823e97aad7beab8a721857c67af88' 
  AND token = 'yBaIepn+crChj8ETcb6/BjLxxg+RZ8x1/5EpVhNy/Sk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}