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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de8b6883b69c0beb40f6a302629f88a8eb6f73e951fe1687153f28b27f74d375' 
  AND token = 'vkS3zzxajtxvO6kEtrzvJfUzce+Tmhc2UT0JPeU6lHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}